In the case of endometrial hyperplasia, what is a recommended management intervention for women who wish to maintain fertility?

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In the context of managing endometrial hyperplasia in women who wish to maintain their fertility, the use of a levonorgestrel intrauterine device (IUD) or progestin therapy is a highly recommended approach. Endometrial hyperplasia often arises due to unopposed estrogen stimulation, leading to an abnormal proliferation of the endometrium. Progestins work by counteracting this effect, promoting the shedding of the endometrial lining and restoring a more normal cyclic pattern.

Levonorgestrel IUDs deliver a local dose of progesterone directly to the uterine lining, which not only helps in reversing hyperplasia but also reduces the risk of progression to endometrial cancer. This treatment is particularly beneficial for women who are looking to conceive in the future, as it allows for the preservation of the uterus and a potential return to a normal ovulatory cycle.

This management option is a conservative treatment that addresses the hyperplasia while providing an opportunity for the woman to attempt to conceive. Therefore, it is considered the best intervention for those who desire to maintain their fertility in the face of endometrial hyperplasia.

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