What is the dosage of Rh D immune globulin given to an Rh-negative patient experiencing a spontaneous abortion?

In cases of spontaneous abortion, it is crucial to administer Rh D immune globulin to an Rh-negative patient to prevent Rh sensitization. The dosage recommended in this scenario is 300 µg, as this amount effectively provides protection against potential complications in subsequent pregnancies.

This dosage is particularly important during the first trimester when the risk of sensitization is higher due to the possibility of fetal Rh-positive blood entering the maternal circulation. Administering the correct dose of Rh D immune globulin after a spontaneous abortion mitigates the risk of the mother’s immune system producing antibodies against Rh-positive blood, which could lead to hemolytic disease of the newborn in future pregnancies.

The other options, which reflect lower dosages, do not provide sufficient coverage in this context. Therefore, the choice of 300 µg aligns with standard clinical protocols to ensure maternal and fetal health.