Which of the following antibiotics is commonly used to treat chorioamnionitis?

The treatment of chorioamnionitis, an infection of the placental tissues and amniotic fluid, often requires the use of broad-spectrum antibiotics to effectively cover a range of possible pathogens. Ampicillin plus gentamicin is the standard regimen for managing this condition.

Ampicillin is a penicillin-type antibiotic that works effectively against common bacteria associated with this infection, including various gram-positive and some gram-negative organisms. Gentamicin, an aminoglycoside antibiotic, provides additional coverage, particularly against gram-negative bacteria. The combination is particularly effective in treating infections in the obstetric setting due to its broad spectrum and synergistic effects, which can help ensure both maternal and fetal safety.

Other options listed do not provide the same level of efficacy or are not standard for treating chorioamnionitis. For example, cephalexin, while it is effective against certain bacterial infections, does not cover the breadth of organisms typically involved in chorioamnionitis. Azithromycin is mainly used for atypical infections and does not have the appropriate coverage for this condition. Metronidazole is primarily effective against anaerobic bacteria and does not encompass the range of pathogens commonly encountered in chorioamnionitis. Thus, the correct choice is am